Talk:2-D/@comment-33799072-20180508172005/@comment-84074-20180508174643

He always had eyes. They're just black due to a condition caused by when Murdoc hit him with a car (twice). The condition is called, Hephyma, and it caused blood to build up in the eyes; sometimes leading to partial or complete blindness.

Going back to your initial question, it could be a creative choice by Jamie to draw him that way for the album cover. For a lore-friendly answer, it could be a trick of the light when the photos were taken or a choice to have some edit 2-D's eyes to make him look at the camera like everyone else.